However, another option is to donate blood on a regular basis. If this occurs patients on the therapy need to lower their dosage or discontinue treatment. Increased testosterone has also been shown to cause polycythemia, an increase in red blood cells, resulting in an increase in blood viscosity. While on TRT patients need to be monitored very closely due to the increased the risk of thrombosis and stroke. Androgel and Testim are examples of prescription topical testosterone and are FDA approved for TRT. FDA approved testosterone therapies include topical gel, transdermal patch, buccal system, and injection. Low testosterone has been linked to an increased risk of cardiovascular disease and mortality as well as associated with symptoms such as depression, decreased sex drive, fatigue, irritability, and decreased muscle mass. Testosterone Replacement Therapy (TRT) is a medically supervised hormone replacement therapy used to alleviate symptoms associated with low testosterone.
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